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However, the mechanism of HBO in HACI has not been systematically elucidated, especially the lack of direct evidence about its effects on the whole genome expression profile and whether and how it targets key pathways such as oxidative stress and neuroinflammation (Bin-Alamer et al., 2024)

Peer review Peer review information Communications Biology thanks Zhi Shi and the other, anonymous, reviewer(s) for their contribution to the peer review of this work